WHO Classification of Tumours of Soft Tissue and Bone. Fourth Edition (2013)

WHO Classification of Soft Tissue and Bone is the fifth volume of the 4th Edition of the WHO series on histological and genetic typing of human tumours. 

This book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. 

The grading of soft tissue tumours has always been a controversial issue. While the WHO does not strictly state a preference in grading systems, one of the major modifications that have been made to the current WHO classification is the designation of two distinct types of intermediate malignancy in terms of biological potential: the "locally aggressive" and the "rarely metastasizing."

Download WHO Classification of Tumours of Soft Tissue and Bone. Fourth Edition (108.4 MB)